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Sincrolab
Resources · Scientific evidence

Validated in clinical trials. Not just promises.

Sincrolab is grounded in scientific studies and medical standards that support its use as a digital treatment to work on attention and cognitive functions.

Main result

Significant improvement in inhibitory control. Measured with the Conners CPT-3.

Conners CPT-3 commission errors (%)
Chart: mean CPT-3 commission error score, pre-treatment versus post-treatment

We found significant differences in the improvement of inhibitory control performance in the Sincrolab treatment group, measured with the Conners CPT-3.

Randomised controlled trial · JMIR 2021Medina R, Bouhaben J, de Ramón I, Cuesta P, Antón-Toro L, Pacios J, Quintero J, Ramos-Quiroga J, Maestú F.Read the study published in JMIR in 2021 

Placebo-controlled randomised trial · npj Mental Health Research, 2025 (p = 0.009):

  • 28%of the treatment group reached the normative range (CPT-C)
  • 0%of the placebo group

Publications

Three peer-reviewed publications. Two of them clinical trials.

npj Mental Health Research · Nature2025Randomised trial

Decreased impulsiveness and MEG normalization after AI-digital therapy in ADHD children: a RCT

AI-driven digital cognitive therapy (12 weeks) versus placebo games. It reduced impulsivity on the CPT-3; 28% normalised their CPT-C, compared with 0% of the control group.

Shpakivska Bilan D., Chicchi Giglioli I.A., Cuesta P. et al.

Read the study published in npj Mental Health Research · Nature in 2025 
Brain Communications2022Controlled study

Alpha-band power increases in posterior brain regions in attention deficit hyperactivity disorder after digital cognitive stimulation treatment: randomized controlled study

First evidence of changes in resting-state alpha oscillations after cognitive stimulation treatment, measured with magnetoencephalography.

de Ramón I., Pacios J., Medina R., Bouhaben J., Cuesta P., Antón-Toro L., Quintero J., Ramos-Quiroga J.A., Maestú F.

Read the study published in Brain Communications in 2022 
J. of Medical Internet Research2021Randomised controlled trial

Electrophysiological Brain Changes Associated With Cognitive Improvement in a Pediatric Attention Deficit Hyperactivity Disorder Digital Artificial Intelligence-Driven Intervention: Randomized Controlled Trial

Cognitive stimulation on a mobile device, driven by an artificial intelligence engine, in children with ADHD.

Medina R., Bouhaben J., de Ramón I. et al. · J Med Internet Res 2021;23(11):e25466

Read the study published in J. of Medical Internet Research in 2021 

An evidence-based treatment

More intervention, better measurement, better outcomes.

Sincrolab isn't a general-purpose app. It's built on neuropsychological models and adapts to the patient's performance in real time, so the intervention carries on beyond the consulting room.

Regulation and quality

Our certificates, for you to check.

Recognised by the media and experts

Research

Would you like to collaborate on our research?

We take an active part in scientific studies to keep building the evidence. If you think Sincrolab could help with your research project, let us know.

What are you interested in?